Healthier life might be found in a specific dose of light

New research suggests that the secret to a longer, healthier life might be found in a specific dose of light. A study published in Lasers in Surgery and Medicine—conducted by the University at Buffalo and the National Institutes of Health—has found that photobiomodulation (PBM) therapy, or light therapy, can significantly delay the onset of age-related heart disease.

Shedding Light on Heart Health

Heart disease remains the leading cause of death in the United States, affecting nearly 20% of seniors. Lead researcher Praveen Arany, Ph.D., DDS, wanted to see if intervening during middle age could prevent the heart from deteriorating as it gets older.

The Findings

The study followed middle-aged mice (14 months old) exposed to low-dose near-infrared light for just two minutes a day, five days a week. The results were remarkable:

• Improved Pumping: The therapy prevented the cardiac wall from thickening and stiffening, keeping the heart’s pumping action effective.
• Better Coordination: Mice showed improved "gait symmetry" on treadmills, indicating better neuromuscular health.
• Drastic Survival Rates: In a group of mice genetically predisposed to fatal heart disease, PBM therapy increased the survival rate from 43% to 100%.

How It Works: The Molecular Trigger

The therapy works by activating a specific substance in the body called transforming growth factor beta (TGF-β1). According to Arany, this protein is a master regulator that controls:

1. Stem cell activity
2. Inflammation
3. Immune system function

By using light to trigger TGF-β1, the researchers were able to "tune" the body's natural healing and maintenance systems.

Safety and Precision

Arany cautions that not all light is created equal. While this study used safe, non-thermal near-infrared LEDs, other types of light (like UV or high-powered lasers) can be damaging. Success of the treatment depends on three "Goldilocks" factors:

• Wavelength: The specific color of the light.
• Intensity: The exact dose delivered.
• Duration: How long the tissue is exposed.

We wanted to see if intervening earlier in life could essentially 'freeze' the heart's condition and avoid the typical decay of old age," Arany explained. What’s Next?

With the success of the animal trials, the research team is now looking toward controlled human clinical trials. If successful, low-dose light therapy could become a non-invasive, everyday tool for maintaining heart health and extending human longevity.

Disclaimer: This content is published only for health awareness and informational purposes. It's not a substitute for your professional medical advice. You must consult a doctor/healthcare professional regarding your specific health concerns.